The Lancet Diabetes & Endocrinology — Bolland MJ, et al. | November 06, 2018
In this systematic review, random-effects meta-analysis, and trial sequential analysis, researchers examined the impact of vitamin D supplementation on fractures, falls, and bone mineral density. An evaluation of 81 trials exhibited no impact of vitamin D supplementation (including higher and lower doses) on fractures, falls, and bone density.
They reported that there is little validation for using vitamin D supplements to preserve or improve musculoskeletal health, and this outcome ought to be reflected in clinical guidelines.