Glucosamine and Chondroitin for Knee Arthritis

From this article, here is the summary of what we think we know in using glucosamine and chondroitin for osteoarthritis:

  • Glucosamine sulfate and glucosamine hydrochloride appear to be equivalent in their efficacy.
  • Individuals with more severe symptoms appear to have a greater response.
  • Those who are obese respond poorly.
  • The average dose for glucosamine is 1500 mg daily, and the average dose for chondroitin is 1200 mg. These can be given once daily or in divided doses.
  • Both supplements have a proven safety record. Glucosamine does not affect serum glucose levels.
  • It can take 6 to 8 weeks for the positive effects to be seen and felt.
  • Glucosamine is made from crustacean shells, and those with a shellfish allergy should avoid it.
  • Chondroitin is often made from bovine trachea (vegetarians beware).

 

August 14, 2014

Clinical Rheumatology

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