Manual Therapy Versus Surgery for Carpal Tunnel Syndrome

In an article published in the journal Physical Therapy, the authors concluded that, in the long-term, manual therapy resulted in similar outcomes as surgery in women with carpal tunnel syndrome. ~ Dr. Broussard

Manual Therapy Versus Surgery for Carpal Tunnel Syndrome: 4-Year Follow-up From a Randomized Controlled Trial

César Fernández-de-las-Peñas
Physical Therapy, pzaa150, https://doi.org/10.1093/ptj/pzaa150
Published: 06 August 2020

Abstract
Objective
No study has investigated the effects longer than 1-year of manual therapy in carpal tunnel syndrome (CTS). The purpose of this study was to investigate the effects of manual therapy versus surgery at 4-year follow-up and to compare the post-study surgery rate in carpal tunnel syndrome CTS.

Methods
This randomized controlled trial was conducted in a tertiary public hospital and included 120 women with CTS who were randomly allocated to manual therapy or surgery. The participants received 3 sessions of physical therapy including desensitization maneuvers of the central nervous system or carpal tunnel release combined with a tendon/nerve gliding exercise program at home. Primary outcome was pain intensity (mean and the worst pain). Secondary outcomes included functional status, symptom severity, and self-perceived improvement measured using a global rating of change scale. Outcomes for this analysis were assessed at baseline, 1 year, and 4 years. The rate of surgical intervention received by each group was assessed throughout the study.

Results
At 4 years, 97 (81%) women completed the study. Between-group changes for all outcomes were not significantly different at 1 year (mean pain: mean difference [MD] = −0.3, 95% CI = −0.9 to 0.3; worst pain: MD = −1.2, 95% CI = −3.6 to 1.2; function: MD = −0.1, 95% CI = −0.4 to 0.2; symptom severity: MD = −0.1, 95% CI = −0.3 to 0.1), and 4 years (mean pain: MD = 0.1, 95% CI = −0.2 to 0.4; worst pain: MD = 0.2, 95% CI = −0.8 to 1.2; function: MD = 0.1, 95% CI = −0.1 to 0.3; symptom severity: MD = 0.2, 95% CI = −0.2 to 0.6). Self-perceived improvement was also similar in both groups. No between-group differences (15% physical therapy versus 13% surgery) in surgery rate were observed during the 4-years.

Conclusions
In the long term, manual therapy including desensitization maneuvers of the central nervous system resulted in similar outcomes and similar surgery rates compared to surgery in women with CTS. Both interventions were combined with a tendon/nerve gliding exercise program at home.

Impact
This is the first study to report clinical outcomes and surgical rates during a 4-year follow-up and will inform decisions regarding surgical versus conservative management of CTS.

Journal Reference