Coenzyme Q10 supplementation for prophylaxis in adult patients with migraine

In an article published in the British Medical Journal, the authors found that CoQ10 didn’t reduce the severity of migraine headaches; however, CoQ10 did reduce the duration and the frequency of migraine attacks. The paper discussed different dosages and I would recommend starting anywhere from 400 mg to 800 mg per day for a minimum of 6 to 8 weeks.  ~ Dr. Broussard

Coenzyme Q10 supplementation for prophylaxis in adult patients with migraine-A meta-analysis

Sazali S, Badrin S, Norhayati MN, et al.
BMJ Open | January 6, 2021

In adult patients with migraine, researchers determined the impacts of coenzyme Q10 (CoQ10), also known as ubiquinone, in reducing the severity and frequency of migraine attacks and the duration of headache in this systematic review and meta-analysis involving 371 participants. This meta-analysis included all randomized control trials contrasting CoQ10 with placebo or using it as an adjunct therapy. Cross-over designs and controlled clinical trials were not included. No statistically significant decrease in migraine headache severity was seen with CoQ10 supplementation. In minimizing the duration and frequency of migraine attacks, CoQ10 seems to have beneficial effects.

Read the full article on BMJ Open.

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