Artificially Sweetened Beverages Increase Women’s Mortality

An article published in the  journal Circulation, they found that the more artificially sweetened beverages that women drank, the higher the risk of death due to cardiovascular disease. ~ Dr. Broussard

Circulation — Malik VS, et al. | May 03, 2019

Among 37,716 men from the Health Professional’s Follow-up Study (HPFS; 1986-2014) and 80,647 women from the Nurses’ Health Study (NHS; 1980-2014), researchers assessed the risk of total and cause-specific mortality in relation to consumption of sugar-sweetened beverages (SSBs) and artificially sweetened beverages (ASBs). Overall, intake of SSBs was positively related to death, primarily through cardiovascular disease (CVD) mortality, and demonstrated a graded link with dose. Among women, investigators found that high intake levels of ASBs were positively associated with total and CVD mortality.

Methods

  • The participants were free from chronic diseases at baseline.
  • They estimated hazard ratios and 95% CIs using Cox proportional hazards regression.

Results

  • They performed 3,415,564 person-years of follow-up, during which time 36,436 deaths (7,896 CVD and 12,380 cancer-related deaths) were reported.
  • Findings revealed the association of SSBs intake with a higher risk of total mortality following the adjustment for major diet and lifestyle factors.
  • The association was evident for CVD mortality and cancer mortality.
  • Only in the highest intake category, was an association of ASBs with total and CVD mortality identified.
  • A link between ASBs and mortality was evident in NHS but not in HPFS in cohort-specific analysis.
  • There was no association of ASBs with cancer mortality in either cohort.

Read the full article on Circulation

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