Magnesium May Help Reduce Frequency of Migraine Headaches

Magnesium may reduce the need for hospitalization during pregnancy, reduce frequency of migraine headaches, and may lower incidence of type 2 diabetes. Here’s a link to the Cleveland Clinic’s website where they list some magnesium rich foods~ Dr. Broussard

Magnesium and health outcomes: an umbrella review of systematic reviews and meta-analyses of observational and intervention studies

European Journal of Nutrition

pp 1–10

Original Contribution
First Online: 25 January 2019

Nicola Veronese

Abstract
Purpose
To map and grade all health outcomes associated with magnesium (Mg) intake and supplementation using an umbrella review.

Methods
Umbrella review of systematic reviews with meta-analyses of observational studies and randomized controlled trials (RCTs) using placebo/no intervention as control group. We assessed meta-analyses of observational studies based on random-effect summary effect sizes and their p values, 95% prediction intervals, heterogeneity, small-study effects and excess significance. For meta-analyses of RCTs, outcomes with a random-effect p value < 0.005 and a high-GRADE assessment were classified as strong evidence.

Results
From 2048 abstracts, 16 meta-analyses and 55 independent outcomes were included (36 in RCTs and 19 in observational studies). In RCTs of Mg versus placebo/no active treatment, 12 over 36 outcomes reported significant results (p < 0.05). A strong evidence for decreased need for hospitalization in pregnancy and for decreased risk of frequency and intensity of migraine relapses in people with migraine was observed using the GRADE assessment. In observational studies, 9/19 outcomes were significant (p < 0.05). However, only one outcome presented highly suggestive evidence (lower incidence of type 2 diabetes in people with higher Mg intake at baseline) and one suggestive (lower incidence of stroke associated with higher Mg intake at baseline).

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