Pro-inflammatory Diet and Depression

The typical American diet is deficient in fruits and vegetables and contains excessive amounts of meat, refined grain products, and dessert foods. Such a diet can have numerous adverse biochemical effects, all of which create a proinflammatory state.  In this study, they relate chronic inflammation due to diet to the risk of depression in women, middle-age adults and overweight or obese individuals. ~ Dr. Broussard

The inflammatory potential of the diet is directly associated with incident depressive symptoms among French adults

The Journal of Nutrition — Adjibade M, et al. | June 04, 2019

Among participants (n=26,730; aged 18–86 years) from the NutriNet-Santé study, researchers assessed the risk of incident depressive symptoms in relation to inflammatory potential of the diet, which was measured using the Alternate Dietary Inflammatory Index. They also investigated whether sex, age, body mass index, and lifestyle indicators had any modulating impact on the aforementioned link. The investigators estimated hazard ratios and 95% CIs using multivariable Cox proportional hazards models. Overall, they found a higher risk of depressive symptoms in relation to a proinflammatory diet, and this link was particularly pronounced among women, middle-age adults, and overweight or obese individuals. These findings, therefore, support prior scientific evidence that demonstrate the detrimental role of proinflammatory diet.

Story Source

Journal Reference